An oral spray called Sativex, which is a combination of THC and CBD, is approved in several countries to treat pain related to multiple sclerosis. There are a number of forms of CBD oil, including softgel capsules, tinctures, and under-the-tongue sprays. Some forms of CBD oil can also be applied directly. Here, learn more about CBD oil and its uses, benefits, and risks. Some products are available as sprays to be administered under the tongue.
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Cannabidiol CBD is a naturally occurring chemical compound found in the hemp plant. It is one of the numerous unique compounds called cannabinoids which naturally occur in hemp. Generally, cannabinoids can be produced in the body these are known as endocannabinoids or found in the hemp plant as phytocannabinoids. CBD is a phytocannabinoid which helps to stimulate the regulation of the central nervous system.
CBD, therefore, helps supplement the effects of endocannabinoids in regulating appetite, mood, functions of the immune system, sensation, and keeping our bodies working normally. CBD oil is made from hemp plants and can be purchased legally in the United States.
CBD is available in different forms such as tinctures, concentrates, capsules, sprays, tapes, and topicals. Both of them represent the commonest compounds found in the plant. However, they have numerous differences. CBD, on the other hand, is not a psychoactive substance as it does not act via the same biological pathways in the body as THC.
Although, CBD oil has not been approved by the FDA for the treatment of any condition, there have been several studies demonstrating some of its health benefits:.
CBD is a non-psychoactive form of cannabinoid which has been found not to interfere with the cognitive functions of the brain. This is mainly because CBD does not contain any addictive substances, in contrast to THC and some cannabinoids which contain such and are, therefore, capable of being addictive.
There have been extensive reviews on the toxic potentials of CBD and reports have revealed that CBD has a relatively low toxicity. It has been found to be safe with little potential for adverse effects. CBD was found to have no effect on fetal development and other bodily functions. However, reports demonstrate that some reactions may occur as a result of its interactions with other drugs co-administered with it. CBD has been found to be effective in the treatment of depression.
While CBD does not cure the condition, it has been linked to improvement of the symptoms. The cannabinoids produced in our bodies endocannabinoids help to regulate several functions of the body such as mood, pain sensation, sleep, and appetite.
These substances exert their actions by binding to specific points of brain cells called the receptors through which they potentiate the actions of a substance called serotonin which acts to improve mood and reduce stress levels.
Serotonin also acts by binding to its receptors in brain cells. When these chemical substances bind to their respective receptors, they trigger a series of events within each brain cell stimulating processes that improve mood and stress control.
CBD has been found to help improve depressive symptoms by modulating the actions of the endocannabinoids and also potentiating the effects of serotonin by enhancing the activity of the receptors unto which serotonin binds.
CBD oil is available in several forms including tinctures, capsules, concentrates, and topical forms. However, it is most commonly administered orally. It is important to note that CBD is most effective when used regularly in maintenance doses, though it may be used for treating acute flare-ups.
In the management of depression, CBD oil may be taken in the tincture and capsule forms. Individuals with depression can begin with a dose of 5 to 10mg daily until the desired results are achieved. Gel capsules of CBD are available as 25mg per pill and it is safe to begin at this dosage as CBD has a good safety profile. The effects of CBD lasts several hours after a dose is ingested and most persons report feeling better for up to 24 hours. However, you will only begin to notice these improvements after 90 minutes of ingestion of CBD oil.
For managing acute flare-ups, it is best to vaporize CBD isolate for fast relief of symptoms. We spoke to experts about the different CBD forms, how they work, and what you can reasonably expect from the experience.
Some people get CBD by smoking the flowering parts of the hemp plant, similar to the way people may smoke marijuana in rolled cigarettes.
Inhaled CBD tends to enter the bloodstream faster than other forms—in as quickly as 30 seconds or less, according to Mitch Earleywine, Ph. The quick action means it should affect the body sooner, which could be especially useful to ease immediate pain or anxiety, for example.
Vape pens are easy to use and can go undetected because they produce little smoke, Raiman says. Note that Oregon and certain other states have laws that prohibit vaping in the same places where smoking cigarettes is prohibited. The CBD cartridges used in vape pens can contain a solvent called propylene glycol, which is also used in e-cigarettes containing nicotine, Earleywine says. At high temperatures, propylene glycol can degrade into formaldehyde, a chemical that can irritate the nose and eyes and could increase the risk of asthma and cancer.
Also, controlling dosing can be particularly difficult with vape pens. How much CBD you absorb depends on how hard and long you inhale, Earleywine says. In addition, labels on vaping devices can be especially confusing, he says. It can be hard to guess what your dosage really is under some of those situations.
Consider trying the lowest dose first—in this case, a single inhale—then wait a few minutes and see whether there is an effect, such as pain relief or reduced anxiety.
If not, try another. And avoid holding your breath after inhaling, because that can irritate the lungs. Tinctures usually in oil form are taken by dropper or spray, straight into your mouth. The CBD used in these forms is extracted from marijuana or hemp plants using pressurized carbon dioxide gas or a solvent such as ethanol.
The solvent is then removed under vacuum, Backes says. The remaining CBD is diluted with an oil, such as sesame or coconut oil, to improve the taste and preserve the cannabidiol. Tinctures are the second-quickest method to absorb CBD, after smoking, Earleywine says, typically taking about 15 to 30 minutes. The quick action could make it especially useful in treating pain or anxiety. If needed, ask a retail salesperson for help or get out your calculator to calculate the amount of CBD per dose.
The price per bottle could be more for a product with a higher CBD content per dose. Earleywine suggests you drop a dose of tincture under your tongue and hold it there for 30 seconds before swallowing, or apply a single spray of the tincture on the inside of your cheeks.
Doing so speeds up the effects of the CBD. If you add a CBD tincture to foods or drinks, it could take up to 30 minutes for it to enter your bloodstream. And ongoing conditions such as chronic pain are likely to better respond with daily doses, he says. Shake the bottle well before using, Backes says, because CBD often gets stuck on the side of the bottle.
Topicals are rubbed directly onto sore muscles or joints, where they may ease pain by reducing inflammation, Earleywine says. CBD balms typically include extracts mixed into a fat, such as beeswax or coconut oil. That recipe not only makes it easier to spread the product on your skin but also allows the CBD to penetrate.
That could make them safer—which could be important if you use CBD on a regular basis—considering how little is known about the long-term safety of CBD and other cannabis products. To be effective, products probably need to have a lot of CBD—which can make them expensive, Backes says. In a retail store, ask whether you can sample the product first, says Tagliaferro of Hemp Garden.
She says some people start feeling effects almost immediately after rubbing it on. Others say they notice relief later in the day, and return to buy the products. At Inday, an East Indian-inspired restaurant in Manhattan, as a promotion, customers could order CBD-infused ghee clarified butter to be added to any dish. Other baked foods, such as brownies and cookies, may have a shorter shelf life and need to be placed in a refrigerator to keep the CBD oil fresh, says Backes, an expert in cannabis science and policy.
You can also consume CBD in pill form. Similar to ingesting CBD in an edible, pills can take upward of 30 minutes or more to digest before you experience an effect, Earleywine says.
One benefit though is that the per-pill CBD dose should be clearer on packaging than for other forms.
Everything you need to know about CBD oil
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