Some plants on this intriguing list do produce actual cannabinoid chemical Believe it or not, many plants beyond cannabis produce phytocannabinoids. Specifically, they engage with the endocannabinoid system (ECS). The plant Cannabis sativa, better known as marijuana, has long been used for Not long after that, another cannabinoid receptor (CBR) was. In the last few years, several other non-cannabinoid plant constituents have been cannabinoid, plant natural products, Cannabis, endocannabinoid system.
Plants, Endocannabinoid System Cannabinoids, Non-Cannabis and the
Refer to Figure 2 to see areas of the brain with cannabinoid receptors , then locate those areas on the chart to study some of the different effects of THC on the user. Locations of Cannabinoid Receptors in the Brain. Breaking Down the Myths http: NIDA for Teens http: The Science of Marijuana: Department of Health and Human Services. Skip to main content. Numerous herbs and teas contain compounds that can enhance the ECS.
Beta-caryophyllene is a terpene found in black pepper, lemon balm, hops, cloves, cannabis, oregano, cinnamon, and several other herbs. It selectively stimulates the CB2 receptor, a sought-after property in the development of treatments for inflammatory disorders. Regular use of moderate to high quantities of alcohol can also impair the ECS  , so for optimal health and endocannabinoid function, please use moderation when drinking or avoid alcohol entirely.
While chronic stress can deplete your ECS, a highly tuned ECS can protect you from the detrimental effects of stress . Incorporating exercise into your daily routine will keep your ECS well-tuned, but only if you enjoy it!
Animal studies teach us that if you force yourself to exercise, your ECS will interpret the activity as stress, but freely choosing and enjoying the same activity can have the opposite effect of stress and actually increase endocannabinoid levels. Socializing can also be great for stress reduction and enhancing ECS function. Rats in social isolation produced less cannabinoid receptors, while social play and grooming behavior increased function of the ECS. The wellness section at Healer.
Endocannabinoids and their receptors are found throughout the body: In each tissue, the cannabinoid system performs different tasks, but the goal is always the same: Your body naturally produces its own cannabinoids.
Proper dosages of cannabis can also up-regulate and tonify your ECS. The plant, however, is not the only way to support your ECS. You can stimulate your ECS naturally with delicious endocannabinoid-enhancing foods and enjoyable activities which can lead to widespread health benefits.
Cannabinoid and Receptor Interaction cell. THC is one of the primary cannabinoids found in the cannabis plant and is largely responsible for the psychological and psychoactive effects brought on from cannabis use [1,8,10].
Over the years based on anecdotal and scientific evidence, THC has demonstrated its potential therapeutic benefit toward a number of conditions and symptoms including nausea, vomiting, insomnia, pain, muscle spasticity, tremors, and bronchospasm often brought on by a range of medical conditions Table 1 [1,8,9,10,11]. Emerging research indicates a high level of therapeutic potential for a variety of health concerns, in some cases even at doses substantially lower than those required to feel the psychoactive effects of THC.
Chemical Structure of THC. CBD is another major cannabinoid found in cannabis. Unlike THC, CBD does not administer the same psychoactive effect s Research is beginning to demonstrate that CBD possesses therapeutic effects through its ability to target several other receptors, including 5-HT1A serotonin receptors, and its blockage of neurotransmitter uptake [2, 4, 15].
It has become increasingly evident that CBD greatly benefits patients suffering from epilepsy by significantly reducing the frequency of re-occurring seizures [1, 6, and 9]. There are several other conditions and related symptoms that have shown to benefit from CBD related therapy see Table 1.
Because of the lack of accompanying psychoactive responses, CBD is often a desirable choice for many individuals seeking cannabinoid therapies without the side effect of impairment. Chemical Structure of CBD. Alternatively, CBD has been shown to treat symptoms of epilepsy [1,6,9], diabetes [5,16], varying symptoms of cancers [5,16], mood disorders including Posttraumatic stress disorder PTSD , Attention deficit disorder ADD , Obsessive-compulsive disorder OCD [9,15], and inflammatory diseases such as arthritis and inflammatory bowel disease IBS [1,16,17,18,20].
In addition, the benefits of CBD may also help with weight management and promote cessation of addictions to smoking tobacco cigarettes [5, 21, 22, 23]. Although the benefits of cannabinoid therapies often differ between THC and CBD, there is often an overlap between the chemicals in which a combination of more than one is preferential. It is important to note that the medical benefits of cannabinoids are not limited to the information displayed in this chart.
The Endocannabinoid System has been shown to affect all regions of the human body and as such is thought to be involved in several ailments including, but not limited to, liver disease, pancreatic disease, obesity, osteoporosis, as well as several joint and movement disorders.
Furthermore, with the current opioid crisis affecting the North Americas there is a necessity for replacement medication. For centuries, Cannabis was widely used without any reservations for its medical benefits.
In fact, the first medical use was reported around BC when the Chinese Emperor Shen Neng prescribed a cannabis tea for several indications including constipation, malaria and memory loss. In BC, the Egyptians used marijuana for glaucoma and enemas while in India it was used as an anesthetic as well as to treat leprosy. By the s, cannabis was particularly popular in Europe as an antidepressant. In the s, when the British colonists arrived in America, they brought over bags of hempseed as the plant was a cash crop.
By the s, medicinal cannabis products were available in the U. Cannabis was published in the US Pharmacopeia in the s for treatment of goat, tonsillitis, anthrax, alcoholism, incontinence and insanity Centennial Presents, The Complete Guide to Medical Marijuana, In , a Lancet publication written by the President of the British Medical Association described its use in several indications including migraine and neuralgia.
Over time and with the development of advanced medicine, to popularity for cannabis decreased. For example the United States Congress introduced the Pure Food and Drug act in which initiated cannabis prohibition. Shortly thereafter, the passing of the Marijuana Tax Act in added another hurdle requiring all purchases to have a tax stamp from the U.
Treasury, who refrained to issue them for cannabis.
What is the endocannabinoid system?
Beyond Cannabis: Plants and the Endocannabinoid System nabinoid tone', a function of the density of cannabinoid receptors, their functional status Trends in Pharmacological Sciences, Month Year, Vol. xx, No. yy. The endocannabinoid system plays many crucial roles in your body, and Not only is the ECS it a natural part of our bodies, it's a crucial one. When someone smokes marijuana, a cannabinoid from the plant attaches to the. The Endocannabinoid System is a signaling pathway that occupies the central Furthermore, CBD activates several non-cannabinoid receptors including the THC is one of the primary cannabinoids found in the cannabis plant and is.